An ardent advocate and passionate performer of contemporary music, Laura Falzon has collaborated with composers from around the world on new works for flute in a variety of combinations, ranging from the conventional flute solo, flute & piano, and flute & orchestra, to works with electroacoustics as well as non-western instruments like the zheng, sitar, tabla, yoruba drums and tanpura. She has commissioned and premiered many flute works including Padma Phool by the Anglo-Indian composer John Mayer (mostly known as the founder of Indo-Jazz Fusion and, in the flute world, for his flute Concerto for Sir James Galway), and other works by composers such as Eddie McGuire, Theodore Wiprud, Mohammed Fairouz, Shirish Korde, Charles Camilleri, Akin Euba, and Geoff Poole.

Her collaborations include work with many musicians such as pianists Timothy Carey, Andrew Ball, Eric Moe, Max Lifchitz, the late Mark Ray & Steve Beck; percussionists Damian Harron of Backbeat percussion ensemble and Doug Perkins of So Percussion; choreographers Sara Pardo and Tanya Bayona Poutiatine; Chinese harpist Zi Lan Liao; conductors Bongani Ndodana and Roger Zahab; sitarist Jonathan Mayer and the late John Mayer, tabla player Dibyarka Chatterjee and many others.